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Tizanidine and a CYP1A2 inhibitor causes hypotension (08-04-2019)

Nashville, 5 April 2019: The commonly used muscle relaxant tizanidine can lower blood pressure. Tizanidine is metabolized by the enzyme CYP1A2, and concurrent use of tizanidine and a CYP1A2 inhibitor, such as ciprofloxacin, greatly increases tizanidine plasma concentrations. Desp......
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Source : Medical Xpress

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